Health Through Horseshoe Crabs

The Value of Blue Blood

The Ramp Rules Horshoe Crabs

Nobility don't literally have blue blood, but horseshoe crabs do, and it's worth quite a bit of money—up to $15,000 per quart.

Horseshoe crabs are ancient critters. We actually consider them living fossils, in that they appear in the fossil record some 450 million years ago.

Though they're called crabs and look like crustaceans, they actually aren't; they're more closely related to spiders. Some species grow to around two feet long. They crawl around on shallow ocean bottoms in sandy and muddy areas, looking for worms and mollusks to eat. They've also been known to eat crustaceans and small fish.

Their blood is a deep, rich blue color due to the presence of hemocyanin—a chemical similar to hemoglobin that carries oxygen through the blood but uses copper instead of iron (which is what makes our blood red). Hemocyanin is somewhat more effective at carrying oxygen in cold, oxygen poor environments than hemoglobin, though hemoglobin is more effective overall.

What really makes the blue blood of horseshoe crabs valuable is how it reacts to disease.

I'm feeling a bit crabby myself.

I'm feeling a bit crabby myself.

Certain cells—called amoebocytes—in the horseshoe crab's immune system are extremely sensitive to bacteria and react by clotting around the infection in an inescapable lump. Pharmaceutical companies burst the cells to harvest coagulogen, the chemical that lets the cells do their thing.

The coagulogen can then be used to detect bacterial contamination in any substance that might come into contact with blood, even at levels as low as one part per trillion. This test has become the absolute standard: every single drug used in the country is required to be tested this way.

This isn't necessarily good for the crabs, though, and the species has also spent quite a bit of time being used as fertilizer and as bait. Over time, this has damaged the population quite a bit.

Though most of the crabs survive the bleeding process, some 15% die and others are rendered too lethargic to mate. All of which is pretty problematic, since they're harvested during mating season.

Scientists are working on an artificial replacement for coagulogen, but that might not help the crabs too much. When science perfects the artificial coagulogen, we’re likely to use our horseshoe crabs as bait.

The Rodney Dangerfield of anthropoids, they just don’t get any respect.

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Quotable

Oh, Yard Ramp Guy, replace “cranky” with “crabby,” and I still claim a blog-specific quotation here:

“I'm cranky.

— Larry David

Scanning for Radiation

Or: Careful with that Shipwreck

McCoy Fields, steel

What do Geiger counters, medical scanners, aeronautical sensors, space sensors, and photon detectors have in common?

If you said that they're all sensors of one sort or another, you're obviously correct. If you said that they're all sensors for detecting radiation, you're even more correct.

In fact, you can list many different traits that they all have in common. They all fit pretty easily into a few categories.

The reason I asked, though, is due to one very specific and shared quirk: they're all largely built out of salvaged shipwrecks.

Each of these devices requires high levels of sensitivity, meaning that they can't be radioactively contaminated themselves—not even a little bit.

Unfortunately, the overwhelming majority of steel we’ve produced worldwide since the Trinity nuclear bomb test (in 1945; the first time humans detonated a nuclear weapon) is contaminated with higher-than-normal levels of radionuclides (radioactive particles) such as Cobalt-60.

McCoy Fields, man of steel

This has been McCoy Fields, man of steel.

This occurs because both the Bessemer process, converting molten pig iron into steel, and the modern BOS steel-making process involve atmospheric gas, with little bits of radioactive particulate drawn in from the atmosphere and planted in the steel.

Though the amount of radioactive materials in the air has dropped drastically since 1963, when nations enacted the Partial Nuclear Test Ban Treaty, radiation still lingers in steel. And we keep recycling our old radioactive steel as scrap metal.

Because of all this, devices that require low levels of radioactive contamination—like our sensors and scanners—can’t use modern steel. Which means that we must use steel produced before the Trinity test.

The best sources of this? Sunken ships—most notably, the scuttled German WWI battleships at Scapa Flow in Scotland.

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Quotable

Oh, Yard Ramp GuyI might just sink your battleship with this one:

“A person without a sense of humor is like a wagon without springs. It’s jolted by every pebble on the road.

— Henry Ward Beecher

The Amazing Spider, Man

Oh, What a Tangled Web We Weave

spider web

If you're not a fan of spiders, you may want to skip this one. Otherwise, I just might’ve already snared you:

Spider silk is one of the most magnificent substances in nature, and there are a ton of different types of spider silk.

The silk can be used to capture prey. Along with their classic web-shaped design, spiders build webs in orbs, tangles, sheets, lace, and domes. One type of spider even lowers single-strand webs to go fishing.

Spiders tie up their prey in webs; a few species actually have venomous webs they use for this purpose. Other spiders produce extremely lightweight webs for “ballooning”—spiders blown along for dozens or even hundreds of miles by the wind, often in enormous swarms. (Yay, Australia!) Others use silk to lay trails to and from their web, and create alarm lines with it.

On top of that, spiders usually are capable of creating multiple types of silk—up to seven types in a single species.

Humans have studied and adapted countless different uses for spider silk. The spider-silk protein is comparable in tensile strength to high-grade alloy steel at one-sixth the density. We have stronger materials, like Kevlar, but none nearly so lightweight. (The strongest spider silk variety is more than ten times stronger than Kevlar.)

Spider silk is extremely stretchy and ductile, retaining its useful properties across a huge temperature range. The silk even makes for excellent bandages, due to its antiseptic qualities, and contains high amounts of vitamin K, which is useful in clotting blood.

Yes, the stuff that spiders spin is extremely useful. So, why don't we use it industrially? Because spider-farming doesn't work. Spiders eat each other. Instead, we've turned to genetic engineering. We've tried altering silkworms, E. Coli, goats (they produced it in their milk), tobacco plants, and potato plants to produce the protein.

We haven't mastered silk well enough to mass-produce, yet, but it'll happen eventually. (And then we'll get spider-web suspension bridges. Completely not creepy!)

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Quotable

Oh, Yard Ramp Guy, weave through this:

“The difference between utility and utility plus beauty is the difference between telephone wires and the spider web.

— Edwin Way Teale

The Missouri-China Connection

Plus: Mud as a Preservative

arabia steamboat mccoy

One of my favorite museums is the Arabia Steamboat Museum in Kansas City, MO. The museum has one of the largest collections of pre-Civil War American artifacts in the world, and it's almost all from the wreck of the Arabia, a paddlewheel steamboat that sank in 1853.

The Arabia was discovered in 1987 by two families that risked everything they owned in their search. Because the Missouri river has shifted over time, they located the Arabia a half-mile away from the river. Excavation began in 1989. Mud preserved the ship almost perfectly.

Artifacts from the Arabia fill the entire museum, which is a huge place that still feels cramped from the size of the collection. The crown jewel of the museum is the actual paddle wheel and driveshaft—and not just sitting there, either. They're both kept in constant motion, though not by the original engine.

While America of the 1800s has a good claim for being the golden age of paddle boats, their use stretches much, much further back in time…and so, naturally, we travel now from Missouri to China.

mccoy fields paddleboatDuring the 1130s in China, the Son Dynasty employed heavy deployment of paddlewheel boats. They weren't steam powered, obviously, but instead driven by pedaled treadmills. Even in the 1130s, paddlewheels weren't new; they'd been in use for a long time, but Yue Fei, the Song general, took them to an entirely new level.

These river-faring paddle ships could carry hundreds of soldiers and sailors, were armor plated, were propelled by up to 24 paddle wheels, and utterly dominated the rivers. The largest of them were armed with immense derricks, capable of swinging wrecking irons against other ships and shore-mounted fortifications, along with deck-mounted trebuchets capable of firing incendiary shells and smoke bombs.

Such ships remain utterly unique in the history of the world. No other civilization has built anything like them. And these weren't the last experiment with paddle-driven warships in China. While the Mongols were besieging a pair of cities linked by a huge pontoon bridge, paddle ships were in ample use by both sides. The Chinese defenders used an immense, hundred-strong fleet of paddle ships to run the blockade, while the Mongols created paddle ships with immense circular saw blades attached to them to cut through the bridge.

This sounds absolutely like something out of a cartoon, but it really worked.

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Quotable

Oh, Yard Ramp Guy, paddle around this one:

“You don't paddle against the current, you paddle with it. And if you get good at it, you throw away the oars.

— Kris Kristofferson